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Peptide transporter DtpA has two alternate conformations, one of which is promoted by inhibitor binding
Peptide transporters (PTRs) of the large PTR family facilitate the uptake of di- and tripeptides to provide cells with amino acids for protein synthesis and for metabolic intermediates. Although several PTRs have been structurally and functionally characterized, how drugs modulate peptide transport...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801073/ https://ncbi.nlm.nih.gov/pubmed/24082128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312959110 |
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