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Physics-based method to validate and repair flaws in protein structures

A method that makes use of information provided by the combination of (13)C(α) and (13)C(β) chemical shifts, computed at the density functional level of theory, enables one to (i) validate, at the residue level, conformations of proteins and detect backbone or side-chain flaws by taking into account...

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Bibliografiske detaljer
Main Authors: Martin, Osvaldo A., Arnautova, Yelena A., Icazatti, Alejandro A., Scheraga, Harold A., Vila, Jorge A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801053/
https://ncbi.nlm.nih.gov/pubmed/24082119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315525110
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