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Assessing the fractions of tautomeric forms of the imidazole ring of histidine in proteins as a function of pH
A method is proposed to determine the fraction of the tautomeric forms of the imidazole ring of histidine in proteins as a function of pH, provided that the observed [Image: see text] and [Image: see text] chemical shifts and the protein structure, or the fraction of H(+) form, are known. This metho...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078339/ https://ncbi.nlm.nih.gov/pubmed/21422292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102373108 |
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