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Use of (13)C(α) chemical shifts for accurate determination of β-sheet structures in solution

A physics-based method, aimed at determining protein structures by using NOE-derived distance constraints together with observed and computed (13)C(α) chemical shifts, is applied to determine the structure of a 20-residue all-β peptide (BS2). The approach makes use of (13)C(α) chemical shifts, compu...

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Detalhes bibliográficos
Main Authors: Vila, Jorge A., Arnautova, Yelena A., Scheraga, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542864/
https://ncbi.nlm.nih.gov/pubmed/18250334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711022105
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