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Use of (13)C(α) Chemical-Shifts in Protein Structure Determination

A physics-based method, aimed at determining protein structures by using NOE-derived distances together with observed and computed (13)C chemical shifts, is proposed. The approach makes use of (13)C(α) chemical shifts, computed at the density functional level of theory, to obtain torsional constrain...

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Hlavní autoři: Vila, Jorge A., Ripoll, Daniel R., Scheraga, Harold A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597024/
https://ncbi.nlm.nih.gov/pubmed/17516673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp0683871
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