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Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair
Recruitment of DNA repair factors and modulation of chromatin structure at sites of DNA double-strand breaks (DSBs) is a complex and highly orchestrated process. We developed a system that can induce DSBs rapidly at defined endogenous sites in mammalian genomes and enables direct assessment of repai...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801049/ https://ncbi.nlm.nih.gov/pubmed/24082117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306160110 |
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