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Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels

P2X receptor channels open in response to the binding of extracellular ATP, a property that is essential for purinergic sensory signaling. Apo and ATP-bound X-ray structures of the detergent-solubilized zebrafish P2X4 receptor provide a blueprint for receptor mechanisms but unexpectedly showed large...

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Detalhes bibliográficos
Principais autores: Heymann, Gabriel, Dai, Jian, Li, Mufeng, Silberberg, Shai D., Zhou, Huan-Xiang, Swartz, Kenton J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801033/
https://ncbi.nlm.nih.gov/pubmed/24082111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311071110
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