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Ion access pathway to the transmembrane pore in P2X receptor channels

P2X receptors are trimeric cation channels that open in response to the binding of adenosine triphosphate (ATP) to a large extracellular domain. The x-ray structure of the P2X4 receptor from zebrafish (zfP2X4) receptor reveals that the extracellular vestibule above the gate opens to the outside thro...

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Hlavní autoři: Kawate, Toshimitsu, Robertson, Janice L., Li, Mufeng, Silberberg, Shai D., Swartz, Kenton J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105519/
https://ncbi.nlm.nih.gov/pubmed/21624948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010593
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