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Pore-opening mechanism in trimeric P2X receptor channels
The opening of ion channels in response to ligand binding, voltage or membrane stretch underlies electrical and chemical signalling throughout biology. Two structural classes of pore-opening mechanisms have been established, including bending of pore-lining helices in the case of tetrameric cation c...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2982178/ https://ncbi.nlm.nih.gov/pubmed/20975702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1048 |
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