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Pore-opening mechanism in trimeric P2X receptor channels

The opening of ion channels in response to ligand binding, voltage or membrane stretch underlies electrical and chemical signalling throughout biology. Two structural classes of pore-opening mechanisms have been established, including bending of pore-lining helices in the case of tetrameric cation c...

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Bibliographic Details
Main Authors: Li, Mufeng, Kawate, Toshimitsu, Silberberg, Shai D., Swartz, Kenton J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982178/
https://ncbi.nlm.nih.gov/pubmed/20975702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1048
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