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Broadly Applicable Methodology for the Rapid and Dosable Small Molecule-Mediated Regulation of Transcription Factors in Human Cells

Direct and selective small molecule control of transcription factor activity is an appealing avenue for elucidating the cell biology mediated by transcriptional programs. However, pharmacologic tools to modulate transcription factor activity are scarce because transcription factors are not readily a...

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Bibliographic Details
Main Authors: Shoulders, Matthew D., Ryno, Lisa M., Cooley, Christina B., Kelly, Jeffery W., Wiseman, R. Luke
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800244/
https://ncbi.nlm.nih.gov/pubmed/23682758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja402756p
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