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APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein, RAP
Amyloid precursor protein (APP) and its secreted form, sAPP, contribute to the development of neurons in hippocampus, a brain region critical for learning and memory. Full-length APP binds the low-density lipoprotein receptor-related protein (LRP), which stimulates APP endocytosis. LRP also contribu...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3800135/ https://ncbi.nlm.nih.gov/pubmed/23061396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12051 |
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