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APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein, RAP

Amyloid precursor protein (APP) and its secreted form, sAPP, contribute to the development of neurons in hippocampus, a brain region critical for learning and memory. Full-length APP binds the low-density lipoprotein receptor-related protein (LRP), which stimulates APP endocytosis. LRP also contribu...

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Detalhes bibliográficos
Main Authors: Billnitzer, Andrew J., Barskaya, Irina, Yin, Cailing, Perez, Ruth G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800135/
https://ncbi.nlm.nih.gov/pubmed/23061396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12051
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