Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA.
We have analyzed the level of intraindividual sequence variability (heteroplasmy) of mtDNA in human brain by denaturing gradient gel electrophoresis and sequencing. Single base substitutions, as well as insertions or deletions of single bases, were numerous in the noncoding control region (D-loop),...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1996
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12382 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|
