Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA.
We have analyzed the level of intraindividual sequence variability (heteroplasmy) of mtDNA in human brain by denaturing gradient gel electrophoresis and sequencing. Single base substitutions, as well as insertions or deletions of single bases, were numerous in the noncoding control region (D-loop),...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
|---|---|
| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1996
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12382 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|