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Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation

Human immunodeficiency virus (HIV) infection associated neurocognitive disorders (HAND) is accompanied with brain atrophy. In these patients, impairment of adult neurogenesis and neurite outgrowth in the hippocampus may contribute to the cognitive dysfunction. Although running exercises can enhance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Myoung-Hwa, Amin, Niranjana D., Venkatesan, Arun, Wang, Tongguang, Tyagi, Richa, Pant, Harish C., Nath, Avindra
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799978/
https://ncbi.nlm.nih.gov/pubmed/23982957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-013-0194-6
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