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Differential involvement of p38 and JNK MAP kinases in HIV-1 Tat and gp120-induced apoptosis and neurite degeneration in striatal neurons
The role of p38 and c-jun-N-terminal kinases 1/2 (JNK), members of the mitogen-activated protein kinase (MAPK) family, in mediating the toxic effects of HIV-1 Tat and gp120 were explored in primary mouse striatal neurons in vitro. Both Tat and gp120 caused significant increases in p38 and JNK MAPK p...
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| Publicado no: | Neuroscience |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310730/ https://ncbi.nlm.nih.gov/pubmed/16111829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2005.05.028 |
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