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Apoptotic death of striatal neurons induced by HIV-1 Tat and gp120: differential involvement of caspase-3 and endonuclease G

Human immunodeficiency virus-1 (HIV-1) infection affects the striatum resulting in gliosis and neuronal losses. To determine whether HIV-1 proteins induce striatal neurotoxicity through an apoptotic mechanism, mouse striatal neurons isolated on embryonic day 15 and the effects of HIV-1 Tat(1-72) and...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Singh, Indrapal N., Goody, Robin J., Dean, Celeste, Ahmad, Nael M., Lutz, Sarah E., Knapp, Pamela E., Nath, Avindra, Hauser, Kurt F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309288/
https://ncbi.nlm.nih.gov/pubmed/15204919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280490441103
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