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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Mutations in superoxide dismutase-1 (SOD1) cause a form of the fatal paralytic disorder amyotrophic lateral sclerosis (ALS), presumably by a combination of cell-autonomous and non–cell-autonomous processes. Here, we show that expression of mutated human SOD1 in primary mouse spinal motor neurons doe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nagai, Makiko, Re, Diane B, Nagata, Tetsuya, Chalazonitis, Alcmène, Jessell, Thomas M, Wichterle, Hynek, Przedborski, Serge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799799/
https://ncbi.nlm.nih.gov/pubmed/17435755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1876
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