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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
Mutations in superoxide dismutase-1 (SOD1) cause a form of the fatal paralytic disorder amyotrophic lateral sclerosis (ALS), presumably by a combination of cell-autonomous and non–cell-autonomous processes. Here, we show that expression of mutated human SOD1 in primary mouse spinal motor neurons doe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799799/ https://ncbi.nlm.nih.gov/pubmed/17435755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1876 |
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