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NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin

Previous reports have shown that activation of N-methyl-D-aspartate (NMDA) receptors potentiates responses to activation of the group I metabotropic glutamate receptor mGluR5 by reversing PKC-mediated desensitization of this receptor. NMDA-induced reversal of mGluR5 desensitization is dependent on a...

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Detalhes bibliográficos
Main Authors: Alagarsamy, Sudar, Saugstad, Julie, Warren, Lee, Mansuy, Isabelle M., Gereau, Robert W., Conn, P. Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799794/
https://ncbi.nlm.nih.gov/pubmed/16005030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2005.05.005
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