Secretory Phosphatases Deficient Mutant of Mycobacterium tuberculosis Imparts Protection at the Primary Site of Infection in Guinea Pigs

BACKGROUND: The failure of Mycobacterium bovis Bacille Calmette-Guérin to impart satisfactory protection against adult pulmonary tuberculosis has necessitated the development of more effective TB vaccines. The assumption that the vaccine strain should be antigenically as similar as possible to the d...

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Main Authors: Chauhan, Priyanka, Reddy, P. Vineel, Singh, Ramandeep, Jaisinghani, Neetika, Gandotra, Sheetal, Tyagi, Anil K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799640/
https://ncbi.nlm.nih.gov/pubmed/24205032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077930
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