Sustained NF-κB Activation and Inhibition in β-Cells Have Minimal Effects on Function and Islet Transplant Outcomes

The activation of the transcription factor NF-κB leads to changes in expression of many genes in pancreatic β-cells. However, the role of NF-κB activation in islet transplantation has not been fully elucidated. The aim of the present study was to investigate whether the state of NF-κB activation wou...

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Główni autorzy: King, Aileen J. F., Guo, Yongjing, Cai, Dongsheng, Hollister-Lock, Jennifer, Morris, Brooke, Salvatori, Alison, Corbett, John A., Bonner-Weir, Susan, Shoelson, Steven E., Weir, Gordon C.
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2013
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799630/
https://ncbi.nlm.nih.gov/pubmed/24204831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077452
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