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Heterogeneous staining: a tool for studies of how fluorescent dyes affect the physical properties of DNA
The commonly used fluorescent dye YOYO-1 (YOYO) has, using bulk techniques, been demonstrated to stain DNA heterogeneously at substoichiometric concentrations. We here, using nanofluidic channels and fluorescence microscopy, investigate the heterogeneous staining on the single DNA molecule level and...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799460/ https://ncbi.nlm.nih.gov/pubmed/23975199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt755 |
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