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Heterogeneous staining: a tool for studies of how fluorescent dyes affect the physical properties of DNA
The commonly used fluorescent dye YOYO-1 (YOYO) has, using bulk techniques, been demonstrated to stain DNA heterogeneously at substoichiometric concentrations. We here, using nanofluidic channels and fluorescence microscopy, investigate the heterogeneous staining on the single DNA molecule level and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799460/ https://ncbi.nlm.nih.gov/pubmed/23975199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt755 |
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