RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes

The role of the mRNA-binding protein human antigen R (HuR) in stabilization and translation of AU-rich elements (ARE) containing mRNAs is well established. However, the trafficking of HuR and bound mRNA cargo, which comprises a fundamental requirement for the aforementioned HuR functions is only poo...

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Bibliographic Details
Main Authors: Doller, Anke, Schulz, Sebastian, Pfeilschifter, Josef, Eberhardt, Wolfgang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799433/
https://ncbi.nlm.nih.gov/pubmed/23921630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt663
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