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Many disease-associated variants of hTERT retain high telomerase enzymatic activity
Mutations in the gene for telomerase reverse transcriptase (hTERT) are associated with diseases including dyskeratosis congenita, aplastic anemia, pulmonary fibrosis and cancer. Understanding the molecular basis of these telomerase-associated diseases requires dependable quantitative measurements of...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799428/ https://ncbi.nlm.nih.gov/pubmed/23901009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt653 |
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