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Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation

Recent studies suggest that induced neuronal (iN) cells that are directly transdifferentiated from nonneuronal cells provide a powerful opportunity to examine neuropsychiatric diseases. However, the validity of using this approach to examine disease-specific changes has not been demonstrated. Here,...

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Détails bibliographiques
Auteurs principaux: Chanda, Soham, Marro, Samuele, Wernig, Marius, Südhof, Thomas C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799342/
https://ncbi.nlm.nih.gov/pubmed/24046374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316240110
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