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Generation of oligodendroglial cells by direct lineage conversion

Transplantation of oligodendrocyte precursor cells (OPCs) is a promising potential therapeutic strategy for diseases affecting myelin. However, the derivation of engraftable OPCs from human pluripotent stem cells has proven difficult and primary OPCs are not readily available. Here we report the gen...

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Hlavní autoři: Yang, Nan, Zuchero, J. Bradley, Ahlenius, Henrik, Marro, Samuele, Ng, Yi Han, Vierbuchen, Thomas, Hawkins, John S., Geissler, Richard, Barres, Ben A., Wernig, Marius
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677690/
https://ncbi.nlm.nih.gov/pubmed/23584610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2564
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