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Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

We recently showed that defined sets of transcription factors are sufficient to convert mouse and human fibroblasts directly into cells resembling functional neurons, referred to as “induced neuronal” (iN) cells. For some applications however, it would be desirable to convert fibroblasts into prolif...

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Autors principals: Lujan, Ernesto, Chanda, Soham, Ahlenius, Henrik, Südhof, Thomas C., Wernig, Marius
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289376/
https://ncbi.nlm.nih.gov/pubmed/22308465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121003109
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