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Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

We recently showed that defined sets of transcription factors are sufficient to convert mouse and human fibroblasts directly into cells resembling functional neurons, referred to as “induced neuronal” (iN) cells. For some applications however, it would be desirable to convert fibroblasts into prolif...

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Détails bibliographiques
Auteurs principaux: Lujan, Ernesto, Chanda, Soham, Ahlenius, Henrik, Südhof, Thomas C., Wernig, Marius
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289376/
https://ncbi.nlm.nih.gov/pubmed/22308465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121003109
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