Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion

Degeneration of midbrain dopaminergic (DA) neurons is a key pathological event of Parkinson’s disease (PD). Limited adult dopaminergic neurogenesis has led to novel therapeutic strategies such as transplantation of dopaminergic precursors (DPs). However, this strategy is currently restrained by a la...

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Publicado no:Sci Rep
Main Authors: Tian, Changhai, Li, Yuju, Huang, Yunlong, Wang, Yongxiang, Chen, Dapeng, Liu, Jinxu, Deng, Xiaobei, Sun, Lijun, Anderson, Kristi, Qi, Xinrui, Li, Yulong, Lee Mosley, R., Chen, Xiangmei, Huang, Jian, Zheng, Jialin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519786/
https://ncbi.nlm.nih.gov/pubmed/26224135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12622
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