Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion

Degeneration of midbrain dopaminergic (DA) neurons is a key pathological event of Parkinson’s disease (PD). Limited adult dopaminergic neurogenesis has led to novel therapeutic strategies such as transplantation of dopaminergic precursors (DPs). However, this strategy is currently restrained by a la...

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Vydáno v:Sci Rep
Hlavní autoři: Tian, Changhai, Li, Yuju, Huang, Yunlong, Wang, Yongxiang, Chen, Dapeng, Liu, Jinxu, Deng, Xiaobei, Sun, Lijun, Anderson, Kristi, Qi, Xinrui, Li, Yulong, Lee Mosley, R., Chen, Xiangmei, Huang, Jian, Zheng, Jialin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519786/
https://ncbi.nlm.nih.gov/pubmed/26224135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12622
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