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Therapeutic enhancement of S-1 with CPT-11 through down-regulation of thymidylate synthase in bladder cancer
Thymidylate synthase (TS), a target enzyme of 5-fluorouracil (5-FU), is significantly associated with prognosis in various cancers. Recently, it has been reported that S-1, a novel 5-FU-based agent has an effect on bladder cancer. However, in cells with high TS level, S-1 did not have significant ef...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799283/ https://ncbi.nlm.nih.gov/pubmed/24156021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.95 |
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