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Potent increased risk of the initiation of DNA replication in human prostate cancer with the use of 5α-reductase inhibitors

Recent clinical studies have raised the clinically important question of the relationship between dihydrotestosterone (DHT) and prostate cancer (PCa) progression. The significance of DHT or 5α-reductase inhibitors (5ARI) in PCa development and progression has not yet been fully characterized. The ai...

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Pubblicato in:Am J Clin Exp Urol
Autori principali: Kosaka, Takeo, Yasumizu, Yota, Miyazaki, Yasumasa, Miyajima, Akira, Kikuchi, Eiji, Oya, Mototsugu
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219299/
https://ncbi.nlm.nih.gov/pubmed/25374915
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