Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas

Metalloproteinases are membrane-bound proteins that play a role in the cellular responses to antiglioma therapy. Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14). To investigate the role of...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ulasov, Ilya, Thaci, Bart, Sarvaiya, Purvaba, Yi, Ruiyang, Guo, Donna, Auffinger, Brenda, Pytel, Peter, Zhang, Lingjiao, Kim, Chung Kwon, Borovjagin, Anton, Dey, Mahua, Han, Yu, Baryshnikov, Anatoly Y, Lesniak, Maciej S
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2013
Sujets:
Cancer Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799280/
https://ncbi.nlm.nih.gov/pubmed/24156018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.104
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