Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas

Metalloproteinases are membrane-bound proteins that play a role in the cellular responses to antiglioma therapy. Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14). To investigate the role of...

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Bibliografiske detaljer
Main Authors: Ulasov, Ilya, Thaci, Bart, Sarvaiya, Purvaba, Yi, Ruiyang, Guo, Donna, Auffinger, Brenda, Pytel, Peter, Zhang, Lingjiao, Kim, Chung Kwon, Borovjagin, Anton, Dey, Mahua, Han, Yu, Baryshnikov, Anatoly Y, Lesniak, Maciej S
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2013
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799280/
https://ncbi.nlm.nih.gov/pubmed/24156018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.104
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