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Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas

Metalloproteinases are membrane-bound proteins that play a role in the cellular responses to antiglioma therapy. Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14). To investigate the role of...

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Detalhes bibliográficos
Main Authors: Ulasov, Ilya, Thaci, Bart, Sarvaiya, Purvaba, Yi, Ruiyang, Guo, Donna, Auffinger, Brenda, Pytel, Peter, Zhang, Lingjiao, Kim, Chung Kwon, Borovjagin, Anton, Dey, Mahua, Han, Yu, Baryshnikov, Anatoly Y, Lesniak, Maciej S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799280/
https://ncbi.nlm.nih.gov/pubmed/24156018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.104
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