Genomic Analysis of a Novel Spontaneous Albino C57BL/6N Mouse Strain

Summary: We report an albino C57BL/6N mouse strain carrying a spontaneous mutation in the tyrosinase gene (C57BL/6N-Tyr(cWTSI)). Deep whole genome sequencing of founder mice revealed very little divergence from C57BL/6NJ and C57BL/6N (Taconic). This coisogenic strain will be of great utility for the...

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Detalhes bibliográficos
Main Authors: Ryder, Edward, Wong, Kim, Gleeson, Diane, Keane, Thomas M, Sethi, Debarati, Vyas, Sapna, Wardle-Jones, Hannah, Bussell, James N, Houghton, Richard, Salisbury, Jennifer, Harvey, Nina, Adams, David J, Ramirez-Solis, Ramiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Technology Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799019/
https://ncbi.nlm.nih.gov/pubmed/23620107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22398
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