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Diminished leptin signaling can alter circadian rhythm of metabolic activity and feeding

Leptin, a hormone mainly produced by fat cells, shows cell-specific effects to regulate feeding and metabolic activities. We propose that an important feature of metabolic dysregulation resulting in obesity is the loss of the circadian rhythm of biopotentials. This was tested in the pan-leptin recep...

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Detalhes bibliográficos
Main Authors: Hsuchou, Hung, Wang, Yuping, Cornelissen-Guillaume, Germaine G., Kastin, Abba J., Jang, Eunjin, Halberg, Franz, Pan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798820/
https://ncbi.nlm.nih.gov/pubmed/23869060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00630.2013
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