Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity

To determine how astrocytic leptin signaling regulates the physiological response of mice to diet-induced obesity (DIO), we performed metabolic analyses and hypothalamic leptin signaling assays on astrocytic leptin-receptor knockout (ALKO) mice in which astrocytes lack functional leptin receptor (Ob...

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Bibliografiske detaljer
Main Authors: Jayaram, Bhavaani, Pan, Weihong, Wang, Yuping, Hsuchou, Hung, Mace, Aurelien, Cornelissen-Guillaume, Germaine G., Mishra, Pramod K., Koza, Robert A., Kastin, Abba J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615600/
https://ncbi.nlm.nih.gov/pubmed/23329815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01499.2012
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