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Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity
To determine how astrocytic leptin signaling regulates the physiological response of mice to diet-induced obesity (DIO), we performed metabolic analyses and hypothalamic leptin signaling assays on astrocytic leptin-receptor knockout (ALKO) mice in which astrocytes lack functional leptin receptor (Ob...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615600/ https://ncbi.nlm.nih.gov/pubmed/23329815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01499.2012 |
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