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Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting cuct
Aldosterone increases tubular Na(+) absorption largely by increasing α-epithelial Na(+) channel (αENaC) transcription in collecting duct principal cells. How aldosterone reprograms basal αENaC transcription to high-level activity in the collecting duct is incompletely understood. Promoter methylatio...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798741/ https://ncbi.nlm.nih.gov/pubmed/23926181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00407.2013 |
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