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Cysteine 96 of Ntcp is responsible for NO-mediated inhibition of taurocholate uptake
The Na(+) taurocholate (TC) cotransporting polypeptide Ntcp/NTCP mediates TC uptake across the sinusoidal membrane of hepatocytes. Previously, we demonstrated that nitric oxide (NO) inhibits TC uptake through S-nitrosylation of a cysteine residue. Our current aim was to determine which of the eight...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798720/ https://ncbi.nlm.nih.gov/pubmed/23886862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00089.2013 |
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