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Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4

Skeletal muscle denervation causes muscle atrophy via complex molecular mechanisms that are not well understood. To better understand these mechanisms, we investigated how muscle denervation increases growth arrest and DNA damage-inducible 45α (Gadd45a) mRNA in skeletal muscle. Previous studies esta...

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Détails bibliographiques
Auteurs principaux: Bongers, Kale S., Fox, Daniel K., Ebert, Scott M., Kunkel, Steven D., Dyle, Michael C., Bullard, Steven A., Dierdorff, Jason M., Adams, Christopher M.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798708/
https://ncbi.nlm.nih.gov/pubmed/23941879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00380.2013
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