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Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4

Skeletal muscle denervation causes muscle atrophy via complex molecular mechanisms that are not well understood. To better understand these mechanisms, we investigated how muscle denervation increases growth arrest and DNA damage-inducible 45α (Gadd45a) mRNA in skeletal muscle. Previous studies esta...

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Autors principals: Bongers, Kale S., Fox, Daniel K., Ebert, Scott M., Kunkel, Steven D., Dyle, Michael C., Bullard, Steven A., Dierdorff, Jason M., Adams, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798708/
https://ncbi.nlm.nih.gov/pubmed/23941879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00380.2013
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