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GCN2 regulates the CCAAT enhancer binding protein beta and hepatic gluconeogenesis

Mice deficient for general control nondepressible-2 (Gcn2) either globally or specifically in the liver display reduced capacity to maintain glucose homeostasis during fasting, suggesting the hypothesis that GCN2 may regulate gluconeogenesis (GNG), which normally plays a key role maintaining periphe...

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Detalhes bibliográficos
Main Authors: Xu, Xu, Hu, Jingjie, McGrath, Barbara C., Cavener, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798698/
https://ncbi.nlm.nih.gov/pubmed/23900421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00063.2013
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