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AMP-activated protein kinase mediates myogenin expression and myogenesis via histone deacetylase 5
There is a global epidemic of obesity, and obesity is known to inhibit AMP-activated protein kinase (AMPK) activity and impairs myogenesis. Myogenin mediates the fusion of myoblasts into myotubes, a critical step in myogenesis. We observed that inhibition of AMPKα1 downregulates myogenin expression...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798682/ https://ncbi.nlm.nih.gov/pubmed/23926128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00124.2013 |
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