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AMP-Activated Protein Kinase α1 but Not α2 Catalytic Subunit Potentiates Myogenin Expression and Myogenesis

The link between AMP-activated protein kinase (AMPK) and myogenesis remains poorly defined. AMPK has two catalytic α subunits, α1 and α2. We postulated that AMPK promotes myogenesis in an isoform-specific manner. Primary myoblasts were prepared from AMPK knockout (KO) mice and AMPK conditional KO mi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fu, Xing, Zhao, Jun-Xing, Zhu, Mei-Jun, Foretz, Marc, Viollet, Benoit, Dodson, Mike V., Du, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838187/
https://ncbi.nlm.nih.gov/pubmed/24043309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01078-13
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