Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation

In fibrotic liver, connective tissue growth factor (CTGF) is constantly expressed in activated hepatic stellate cells (HSCs) and acts downstream of TGF-β to modulate extracellular matrix production. Distinct from other cell types in which Smad signaling plays major role in regulating CTGF production...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Liu, Yan, Liu, Heng, Meyer, Christoph, Li, Jun, Nadalin, Silvio, Königsrainer, Alfred, Weng, Honglei, Dooley, Steven, ten Dijke, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798541/
https://ncbi.nlm.nih.gov/pubmed/24005672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.478685
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars