Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation

In fibrotic liver, connective tissue growth factor (CTGF) is constantly expressed in activated hepatic stellate cells (HSCs) and acts downstream of TGF-β to modulate extracellular matrix production. Distinct from other cell types in which Smad signaling plays major role in regulating CTGF production...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Yan, Liu, Heng, Meyer, Christoph, Li, Jun, Nadalin, Silvio, Königsrainer, Alfred, Weng, Honglei, Dooley, Steven, ten Dijke, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798541/
https://ncbi.nlm.nih.gov/pubmed/24005672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.478685
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados