Cytosolic Carboxypeptidase 5 Removes α- and γ-Linked Glutamates from Tubulin

Cytosolic carboxypeptidase 5 (CCP5) is a member of a subfamily of enzymes that cleave C-terminal and/or side chain amino acids from tubulin. CCP5 was proposed to selectively cleave the branch point of glutamylated tubulin, based on studies involving overexpression of CCP5 in cell lines and detection...

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Main Authors: Berezniuk, Iryna, Lyons, Peter J., Sironi, Juan J., Xiao, Hui, Setou, Mitsutoshi, Angeletti, Ruth H., Ikegami, Koji, Fricker, Lloyd D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Enzymology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798508/
https://ncbi.nlm.nih.gov/pubmed/24022482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.497917
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