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A defect in cytosolic carboxypeptidase 1 (Nna1) causes autophagy in Purkinje cell degeneration mouse brain

Purkinje cell degeneration (pcd) is a mouse mutant which is characterized by post-natal degeneration of selective cell types. The pcd mutation was mapped to a gene encoding a cytosolic carboxypeptidase-like protein (CCP), named CCP1/Nna1. Many neurons in pcd mice show increased levels of autophagy,...

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Bibliografiske detaljer
Main Authors: Berezniuk, Iryna, Fricker, Lloyd D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927707/
https://ncbi.nlm.nih.gov/pubmed/20484972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.4.11813
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