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A defect in cytosolic carboxypeptidase 1 (Nna1) causes autophagy in Purkinje cell degeneration mouse brain
Purkinje cell degeneration (pcd) is a mouse mutant which is characterized by post-natal degeneration of selective cell types. The pcd mutation was mapped to a gene encoding a cytosolic carboxypeptidase-like protein (CCP), named CCP1/Nna1. Many neurons in pcd mice show increased levels of autophagy,...
में बचाया:
| मुख्य लेखकों: | , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927707/ https://ncbi.nlm.nih.gov/pubmed/20484972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.4.11813 |
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