Cytosolic Carboxypeptidase 1 Is Involved in Processing α- and β-Tubulin

The Purkinje cell degeneration (pcd) mouse has a disruption in the gene encoding cytosolic carboxypeptidase 1 (CCP1). This study tested two proposed functions of CCP1: degradation of intracellular peptides and processing of tubulin. Overexpression (2–3-fold) or knockdown (80–90%) of CCP1 in human em...

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Hauptverfasser: Berezniuk, Iryna, Vu, Hang T., Lyons, Peter J., Sironi, Juan J., Xiao, Hui, Burd, Berta, Setou, Mitsutoshi, Angeletti, Ruth H., Ikegami, Koji, Fricker, Lloyd D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307270/
https://ncbi.nlm.nih.gov/pubmed/22170066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.309138
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